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Peyronie's disease is a curve in the penis.

Many men have a slight curve in the penis. As long as there is no pain or problem with sexual performance, men with a slightly curved penis should not be concerned and do not need to see a doctor.

However, some men develop a more serious bend in the penis that interferes with sexual function or causes pain. This occasionally happens after the penis is injured, either during intercourse or from a motor vehicle or industrial accident. Most cases, however, are the result of a poorly understood process known as Peyronie's disease.

In Peyronie's disease, inflammation and scar tissue form along the shaft of the penis. Due to a infection or injury.

Peyronie's disease may occur in up to 1% of the population. Most men with the problem are between the ages of 45 and 60. The disease runs in families and appears more common in white men. In 30% of men, Peyronie's is associated with the formation of scar tissue in other parts of the body, including the palms of the hands (Dupuytren's contracture), the soles of the feet (plantar fibromatosis) and the eardrums (tympanosclerosis).

Sometimes, a serious curvature of the penis is seen in boys at or shortly after birth. This is not Peyronie's disease. Most of these cases are thought to be caused by abnormal development in the womb, and may be associated with other abnormalities of the penis such as a condition called hypospadias, in which the opening of the penis is not at the tip.

About half of men with Peyronie's disease will first notice pain during intercourse. Symptoms may appear suddenly, or may develop slowly over time. Often the penis will feel firm or lumpy at the painful site. Other men with Peyronie's will notice a painless curve of the penis that can occur suddenly or get worse over time. The penis may curve up, down or to either side. Severe changes in the shape of the penis may prevent the man from having intercourse. Men usually seek help from their doctors because of difficulty with intercourse rather than the curvature itself.

If the penis has been injured by sudden trauma, most men will be able to recall the event. Often there will be a sensation or sound of a "snap" followed by loss of erection and the appearance of a bruise. Part of the penis will remain painful for a time, but usually the area will heal over time. However, scar tissue may form and cause a new curvature. This problem is different from Peyronie's, and rarely results in difficulties with erections or shortening of the penis.

Your doctor will ask you about your symptoms and will examine your penis, looking for tender, firm areas of scar tissue (plaques) during a physical examination. 

A curve in the penis that is present since birth or is caused by scarring from an injury will not go away unless it is corrected with surgery.

How long Peyronie's disease lasts is difficult to predict. In more than a third of men, there is gradual improvement over 12 to 18 months without any specific treatment. In others, the scarring is permanent or worsens over time.

There is no way to prevent Peyronie's disease. However, there is some evidence to suggest that middle-aged men who engage in more vigorous or frequent intercourse are more likely to develop Peyronie's.

Most men with curvature of the penis, regardless of the cause, do not need any treatment. Men with Peyronie's disease who experience pain or difficulty with intercourse sometimes are offered medical treatment. Options include the following:

• Oral medications such as vitamin E, para-aminobenzoic acid (a B vitamin) and colchicine (sold as a generic)
• Injections of cortisone or other medications such as verapamil into the scar tissue
• Ultrasound orradiation therapy

In a typical procedure, the inflamed or scarred portion of tissue is removed from the penis and replaced with a graft taken from another part of the body, often the scrotum or forearm.

Call your doctor if:

• You notice new curvature of your penis.
• You experience pain during intercourse.
• You develop difficulties with erections.
• You notice a firm or painful lump on your penis.

One-third to one-half of men with Peyronie's disease improve without treatment.  Only a minority of men eventually will require surgery.

Peyronie's disease never develops into cancer or other serious conditions.