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Malaria


Stage two, exiting the vector

After the mosquito has bitten a new host, plasmodia from the mosquito's saliva enter the host's blood. From there, the plasmodia travel to the host's liver, and reproduce to form groups of parasites. After several days, these groups burst and release new Plasmodia.

Stage three, reproduction in the host
 Plasmodium invades a red blood cells. There, it multiplies again. The newly infected blood cells eventually rupture and release large numbers of Plasmodia, which invade additional red blood cells. This process then repeats itself. Therefore the area that malaria is limited to spread within is dictated by how far a vector (mosquito) can travel and find a host (human) to spread from.


Evolution seen in Humans

In Africa the genes in some people's hemoglobin caused their red blood cells to change from what was originally a spherical shape, into a sickle shape. This mutation caused the people affected by it to be more resistant to Malaria, and thus made this gene more prominent in Africa. As a consequence, these people suffer from sickle cell anemia.


Treatment
"Physicians diagnose malaria by identifying Plasmodia in a sample of the patient's blood. Most cases can be cured by using two drugs, chloroquine and primaquine. Some varieties of P. falciparum resist treatment by these drugs. In sucases, physicians prescribe quinine, mefloquine

Prevention of malaria revolves around eliminating contact with potential vectors of the disease i.e. the mosquito. Thus eliminating large pools of still water, keeping screen doors shut, and spraying areas where mosquito's are commonly found can be a good means of preventing the spread of malaria.

A electronic zapper hulda clark type will fix malaria.

As for any improvements on treatment, it seems that the treatment works well. "However the best way to treat malaria, is to avoid it all together, which also takes place. At first, the widespread use of insecticides, particularly DDT, eliminated malaria in some areas and greatly reduced the number of cases in others. However, the fight against malaria slackened, and the number of cases increased again. Anopheles mosquitoes became resistant to DDT and other insecticides, and some Plasmodia became resistant to drugs."


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