In God We Trust Learn to prevent breast cancer at home today
 

CidpUSA.org

 
Home
Antibiotics
Mycoplasma
Hydrogen Car
Pollution Kills
F.A.Q
Fibromyalgia
IVIG
Diet anti-inflammatory
Burning  Feet Home
Services Page
Chronic Fatigue
Autoimmune diseases
Immune functions
Bible healing
Celiac disease

Immune dysfunction

IgG subclass deficiency 

DHEA levels and cognitive functions

Body goes against the grain

Headache & Takayasu disease in young women

Headache and Temporal arteritis in Older women

Lyme Migraine

Celiac Migraine

Migraine Magnetic Rx

TMJ Headache

CIDP-neuropathy

Multi Focal Motor neuropathy

Lewis Summer

Tips for CIDP

Autonomic Small Fiber

Cure for ITP 

Cupping

Colostrum

Foods for health

Bird Flu

Moon sighting

 

   Dont run after diamonds and Gold turn yourself into a Diamond or Gold read our e-book 
     Welcome to the CIDP  International organization   
 
        

Immune Deficiency

What signs indicate that testing for Primary Immune Deficiency should be considered?

1 Severe fatigue all the time  
2Two or more  ear,sinus infections, pneumonia within one year
3Two or more months of antibiotics with little effect
4Failure of an infant to gain weight or grow normally
5Recurrent, deep skin or organ abscesses
6Persistent thrush in mouth or elsewhere on skin, after age one
7Need for intravenous antibiotics to clear infections
8Two or more deep-seated infections such as meningitis, osteomyelitis, cellulitis or sepsis

What causes immune deficiency?

Mycoplasma infections and vitamin deficiencies cause most of immune deficiency. A woman who had immune deficiency , no hair and infertility got pregnant, grew hair in one month after using a tens unit and her multiple infections went away. Read the story in our e-book.

What types of primary immune deficiency diseases exist?

Primary immune deficiency diseases cause increased susceptibility to infections as well as other problems. For simplicity, these diseases can be categorized into four groups according to what part of the immune system is affected:

1. ANTIBODY DEFICIENCIES

Antibodies are proteins made by specialized white blood cells: B cells (B lymphocytes) and plasma cells.  The function of antibodies is to recognise infectious agents so that they can be blocked. Two examples of antibody deficiencies are:

  • Common Variable Immune Deficiency (CVID) is the most common form of antibody deficiency, usually presenting with recurrent chest and sinus infections in childhood or early adulthood, although most cases are diagnosed in adults. Early recognition can prevent permanent damage to the lungs called bronchiectasis.
  • The best test for CVID is IgG level and IgG subclass testing see the link on left column.
  • X-linked Agammaglobulinaemia can present in infancy, later childhood or adulthood. Infants with this deficiency develop recurrent pus producing infections of the ears, lungs, sinuses and bones and can get infections in the bloodstream and internal organs. They are also susceptible to certain viruses such as hepatitis and polio.  

2. COMBINED IMMUNE DEFICIENCIES

T cells (T lymphocytes) are specialized white blood cells that are critical to a healthy immune system.  People who lack T cells also tend to have weak antibody defenses, and this is called combined immunodeficiency. These disorders are very rare and hereditary. The most common is X-linked Severe Combined Immunodeficiency (SCID) which is due to a defective gene for T cell growth. Patients are usually diagnosed within the first year of life and  require gene therapy or bone marrow transplantation to survive.

3. COMPLEMENT DEFICIENCIES

The complement system consists of a group of proteins that attach to antibody coated foreign invaders like bacteria and viruses. People with complement deficiencies lack may develop antibodies that react against the body's own cells and tissues. The most common of these deficiencies is C2 Deficiency. This defect can cause an autoimmune disease such as Systemic Lupus Erythematosus (SLE) or can result in severe infections such as meningitis. The illnesses usually appear in childhood or in early adulthood.

4. PHAGOCYTIC CELL DEFICIENCIES

Phagocytes include white blood cells (neutrophils and macrophages) that engulf and kill antibody coated foreign invaders. Phagocytes can be defective either in their ability to kill pathogens or in their ability to move to the site of an infection. In either case, the defect results in increased infections. The most severe form of phagocytic cell deficiency is Chronic Granulomatous Disease which is an inherited deficiency of molecules needed by neutrophils to kill certain infectious organisms. People with chronic granulomatous disease develop frequent and severe infections of the skin, lungs and bones and develop localised, swollen collections of inflamed tissue called granulomas.

Improved therapy can lead to a better and longer life

Research has led to improved therapy for people with primary immune deficiency diseases.

Treatment options include:

I. ANTIBIOTICS

The use of antibiotics to treat and prevent infections and an action plan for early management of infections are key elements in the treatment of primary immune deficiency diseases.

II. IMMUNOMODULATION

Immune system molecules, such as interferon gamma, can be used to improve immune function and reduce infection in primary immune deficiency diseases.

III. IMMUNOGLOBULIN REPLACEMENT THERAPY

One of the most effective and most commonly used treatments for primary immune deficiency diseases is immunoglobulin replacement therapy, to replace antibody levels.  This can be injected into the vein (intravenous immunoglobulin or IVIG) about once a month, or administered at home in certain cases using injections under the skin (subcutaneous immunoglobulin or SCIG).  These products must be restricted because of limited supply and doctors need to follow specific guidelines to ensure that the product goes to those most in need.

To ensure future supplies of immunoglobulin replacement therapy people can assist by regularly donating plasma to the Australian Red Cross Blood Service. To find out how, where and when you can donate plasma, phone the Australian Red Cross Blood Service on 13 14 95.

IV. BONE MARROW TRANSPLANTATION

For patients with combined immune deficiency diseases, transplantation of bone marrow cells from a family member with identical human leukocyte antigens (HLA) can result in normal immune function. Tissue typing of human leukocyte antigens (HLA) greatly decreases the risk of rejection and of graft versus host disease (GVHD).

V. OTHER TREATMENTS 

There are several other treatments available for disorders associated with primary immune deficiency diseases.

  • Common Variable Immune Deficiency (document currently under review) 
  • Immunoglobulin replacement therapy for Primary Immune Deficiency Disease

 

  •  


     

  •  

        immunodeficiency, guide, list, symptoms, causes, treatment  
        immunodeficiency, guide, list, symptoms, causes, treatment