God  our Guide  
  

Home
Diagnosis
Treatment
Pathology
Variants
CIDP info
GBS
IVIG
Diet
About Us
Celiac disease
Grain & Disease
Autoimmune diseases
Celiac Info
Anemia in Celiac
Celiac research
 Hearing Loss

CIDP-neuropathy

Multi Focal Motor neuropathy

M.M.F.

Lewis Summer

Tips for CIDP

Axonal EMG

CIDP-EMG

Small Fiber Neuropathy

Plasmapheresis

CIDP-INFO

CIDP-doctors

CIDP-Rituxan

CIDP-GBS-Handbook

CIDP-family issue

CIDP-Cyclosporin

Polyneuropathy

CIDP-GBS children

CIDP-Pork Plant

Peripheral Neuropathy

ALS & CIDP

Types of neuropathy

Treatment of alcoholic poly neuropathy

 

B-12 deficiency

cancer treatment almonds

Bulemia TMS Therapy

Cancer & Chapparal

Silver Filling

Cancer Regan

Magnet Deficiency

Electronic stimulation

HAARP

   EMG AND AXONAL POLYNEUROPATH
  All Natural treatments for all diseases please read this link  

Contact is through services section
Please click the +1 button if you like this page Thanks
 
EMG Findings of Axonal Polyneuropathy                No Biopsy CIDP   
Please also see the complete EMG/NCV section 

 

Question

Does an axonal polyneuropathy necessarily display increased insertional activities? If nerve conduction velocity studies are consistent with an axonal polyneuropathy, can such a diagnosis be made even without fibrillation or positive waves?

Response from  Orly Avitzur, MD, MBA 
Lecturer, Department of Neurology, Yale University School of Medicine, New Haven, Connecticut; Assistant Professor, Department of Neurology, New York Medical College, Valhalla, New York
 

Absolutely. The electrophysiologic characteristics of neuronopathies and axonopathies depend on how long the condition has been present. In the acute states, there is moderate-to-severe denervation, which may include increased insertional activity, positive sharp waves, and fibrillation potentials. But this is often not the case for chronic motor neuronopathies or axonopathies, nor, of course, for sensory or autonomic axonopathies.

Generally, in axonal neuropathies, nerve conduction velocities are normal or slightly decreased; distal latencies are normal or slightly prolonged; but motor potentials and sensory amplitudes are significantly reduced. These changes are more apparent in the lower extremities where a distal pattern is greater than a proximal pattern. Needle electromyography (EMG) studies may detect spontaneous activity, such as increased insertional activity, positive sharp waves, and fibrillation potentials, within weeks, although various patterns develop depending on the tempo of progression. In Chapter 7 ("Clinical Electromyography") of Neuromuscular Disorders in Clinical Practice , Katirji and associates[1] state:

. . . if the process is relatively active and progressive, a combination of denervation with reduced recruitment of reinnervated motor unit action potentials (MUAPs) will be seen, most prominent distally. If, on the other hand, the polyneuropathy is chronic and only very slowly progressive, reinnervation may completely keep pace with denervation. . . and the sole finding on needle EMG is reduced recruitment of reinnervation MUAPs.

 

Brown and coworkers,[2] in Chapter 19 ("Negative Signs and Symptoms of Peripheral Nerve and Muscle Disease") of their textbook Neuromuscular Function and Disease, Basic, Clinical, and Electrodiagnostic Aspects , note that "chronic motor neuronopathies or axonopathies typically exhibit little or no abnormal insertional or fibrillation potential activity or evidence of instabilities of axonal or neuromuscular transmission and their M-potentials may be relatively well preserved, even in the face of severe motor axon losses." They also explain that in such situations, reinnervation probably keeps pace with the rate of axonal loss until the final stages.


References

  1. Katirji B, Kaminski HJ, Preston DC, Ruff RL, Shapiro BE. Neuromuscular Disorders in Clinical Practice . Boston, Mass: Butterworth-Heinemann; 2002.
  2. Brown WF, Bolton CF, Aminoff MJ. Neuromuscular Function and Disease: Basic, Clinical, and Electrodiagnostic Aspects . Philadelphia, Pa: WB Saunders Co.; 2002.
  3. Axonopathies

    Learn about nerves

    Want to learn about nerve physiology?

     

 

The simplest treatment for any neuropathy or CIDP is a gluten free diet, 30-40 % diseasefor reversal. See our celiac section of cidpusa website. We provide cures for ailing humanity.

 

 

 

  Shifa     Subcutaneous IVIg PAGE. Rheumatoid story