Autoimmune diseases

Neuropathy Clinical blood tests
by: Imran Khan, M.BBS |June 29, 2020

 EMG/NCV section

Learn about the Brain

Learn Nerve physiology

 Most diabetic neuropathy is CIDP

Vitamin  Blood tests for neuropathy

Vitamin B12 and B6 ( routine), in selected case (thiamine , E and niacin)  For Niacin there is no blood test follow the niacin link for treatment recommendation.Thiamine deficiency, in particular, is common among people with alcoholism because they often also have poor dietary habits. Thiamine deficiency can cause a painful neuropathy of the extremities

Thyroid, liver and kidney functions ( TSH which will suggest autoimmune disease Vasculitis evaluation (CRP or Sed rate) .

Antibodies to nerve components (anti-MAG, anti-GM1, anti-Sulfatide, anti-GALOP, Anti-GQ1b) do not do if NCV is positive for neuropathy

Antibodies related to celiac disease avoid if patient has low Vitamin D and low iron levels that already points towards Celaic

Lyme disease , ( Borrelia burgdorferi antibodies)

HIV test for AIDS, Syphilis test called (RPR).

Anti-Hu ( antibody for a pure sensory neuropathy underlying malignancy)

 SPEP (For Myeloma)

Only for those patients going on IVIg treatment IgA level ( prevent anaphylaxis), IgG level, IgG subclass levels.

For help see services section link above  EMG /NCV is done in every patient. Those with normal NCV need a skin biopsy for small fiber neuropathy.

There is no need for Nerve Biopsy it is usually a painful process.


I. Khan

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