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HIV Virus


HIV  Diseases

HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus of sheep.
This natural recombinant may have been inadvertently transferred to humans through the Intensified Smallpox Eradication Program conducted in sub-Saharan Africa in the late 1960s and most of the 1970s.

Refrence from Pub-Med

The origin of HIV-1, the AIDS virus

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West J Med. 1994 May;160(5):447-52.Neuromuscular complications of human immunodeficiency virus infection and antiretroviral therapy.

Miller RG.

Department of Neurology, California Pacific Medical Center, San Francisco.

At least 4 distinct peripheral neuropathy syndromes occur in patients infected with the human immunodeficiency virus. The most common, painful sensory neuropathy, may be related to the viral infection or may be =medication induced and is treated symptomatically. The other 3, chronic inflammatory demyelinating polyradiculoneuropathy, mononeuropathy multiplex (some patients), and the progressive polyradiculopathies related to the acquired immunodeficiency syndrome, may all respond to appropriate therapy. Both inflammatory myopathy and zidovudine =myopathy also abate with early diagnosis and treatment.

Visna, a lingering meningo-encephalitis in sheep, was one of the diseases on which B. =Sigurdsson based his theory of a special group of disorders called slow infections. The cause of the disease, a retrovirus, was isolated in 1957. Visna is now classified in a subgroup of retroviridae, lentivirinae, together with virus types in animals and the =human immune deficiency virus HIV. Not withstanding that Visna has been eradicated among Icelandic sheep for 25 years research into this virus continues since it bears many similarities to HIV and also MS.