CIDPUSA for AUTOIMMUNE DISEASES ,  God our Guide

Infection Allergies & Disease

Help for all diseases
By CIDPUSA.ORG,
Sat, 31 May 2010 17:55:07

Reduced Infection Hazard

  


Has Decreased Infection Load Of Infants Led To Increased Allergic And Autoimmune Diseases?

infections

Science research (May 29, 2008)

The starting point of the hygiene hypothesis is that the decreasing infection load of infants in the developed countries leads to an increase in allergic and autoimmune diseases. Such development has been observed practically in all industrialized countries after the Second World War. Now an extensive research project begins to establish how the living environment affects the development and maturation of a child's immune system.High living standards and the life style connected to them seem to promote the development of autoimmune diseases and allergic symptoms. This has lead to the assumption that the immune system begins to overreact to the organism's own structures or to exogenous non-infectious proteins, i.e. allergens, when it does not have to work hard enough to protect the individual from infections.

The European Union with its Seventh Framework Program has allocated 6 million euros to the University of Helsinki coordinated DIABIMMUNE research project for the years 2008-2013 to establish whether the decrease in the infection load is connected to type 1 diabetes and the emergence of allergies.

The project comprises 12 partners from five countries. The study will include 7 000 children from Finland, Estonia and Russian Karelia in northwestern Russia. In each country the study will follow more than 300 children from birth to their 3rd birthday. In addition, the research will focus on 2 000 children from their third to fifth birthdays.

"Earlier we have studied autoimmune phenomena and allergic responses in Finnish and Russian Karelian school children. Now we are to study infants and toddlers in order to yield new information on the maturation of the immune system and the interaction between the immune system and the environment", says Professor Mikael Knip from the University of Helsinki.

Based on earlier studies it is known that the incidence of type 1 diabetes is six times higher and the prevalence of celiac disease five times higher among Finnish children than among Russian Karelian children. The HLA gene variants that predispose people to autoimmune diseases are however approximately equally common in both populations. The studies have also revealed that Russian Karelian school children have helicobacter antibodies as signs of earlier infections 15 times more often, Toxoplasma antibodies five times more often, and hepatitis A antibodies 12 times more often than Finnish children. Karelian children also have considerably more often antibodies against the Coxsackie B4 virus, belonging to the enterovirus group, than Finnish children have.

"The differences in the frequency of autoimmune phenomena and allergic responses between Finland and Russian Karelia cannot be due to genetic causes. High living standards and the associated life style appear to promote the development of autoimmune diseases and allergic responses", Knip says.

The DIABIMMUNE project focuses for example on the development of the intestinal bacterial flora after birth and the effect the living environment has on the composition of the bacterial flora. The research also studies the effect infections have on the maturation of the human immune system and the operation of the white blood cells that regulate immune responses. In addition, the researchers study whether the protection conferred by infections against autoimmune and allergic responses is associated with the overall infection load or due to specific microbes. The project also examines the effect of the child's nutrition on the maturation of the immune system, the intestinal bacterial flora and the occurrence of infections.

"The diseases we are studying are the most common chronic diseases in children and their impact, both societal and medical, is vast. We are searching for ways to stop these diseases from becoming more frequent and to prevent their development", Knip says.

Left Column: see our links CIDPUSA.org
  1. Skin repair Clinic
  2. Magnetic Field
  3. Magnetic Flux
  4. Magnetic stimulator
  5. Magnetic therapy
  6. Pulsed Magnetic
  7. RTMS in depression
  8. Electronic Treatmen
  9. Migraines magnetic
  10. Magnetic map
  11. Antiageing Magnets
  12. Bulimia TMS treatment
  13. Massage Cancer Cure
  14. Hydrogen Peroxide helps human cycles
  15. ACV
  16. Coconut oil Benefits
  17. Vitamin E Guide
  18. Cancer therapy
  19. Healthy Oils
  20. Coconut for health
  21. Cancer cure
  22. Beauty Tips for Women
  23. Kegel
  24. Celiac Disease
  25. Hair rejuvenation
  26. Breast Disease
  27. Quick Heart Cure
  28. Curry Powder
  29. Sulphur Bath
  30. Water chestnut
  31. B-12 deficiency
  32. Spinal Injury
  33. Homeopathic allergy
  34. Renal failure
  35. Top Foods
  36. Alkaline Foods
  37. Colostrum
  38. Spices
  39. Vinegar
  40. SESAME SEED OIL
  41. Tomato as a medicine
  42. Epilepsy diet
  43. Food additives
  44. No artificial sweetener in diet
  45. Loss of appetite
  46. Breast cancer herbs
  47. DeTox diet
  48. Avoid Gum
Right Column: best guidelines in the world neuropathy is easily reversiabe with IVIG. See our IVIG section.